
Your Money Would Be Better Served In A 401(k)
1. Arginine Supplements
Notice I didn't call them nitric oxide supplements. These supplements don't work. That's right I said it. You just spent $50.00 on a one-month supply of the latest arginine supplement and it just doesn't work. The science behind these supplements is shaky at best.
Think about it... so you ingest a bunch of arginine and it somehow finds its way to the muscle that you are working that day. We've all seen the Muscle Tech ads so we know what happens next.
The arginine gets turned into nitric oxide which then activates guanylyl cyclase. Guanylyl cyclease converts GTP into cGMP which then mediates smooth muscle relaxation causing blood vessels to become bigger and increased blood flow.
Here are the questions that I have which make me question these supplements.
- What if the arginine (and arginine precoursors) does not go straight to the muscle being exercised and this incredible vasodilatation (the one that causes "mind blowing pumps") occurs somewhere else or maybe everywhere. Couldn't this possibly lead to hypotension (a drop in blood pressure)?
- Nitric Oxide is a nasty free radical with an extremely short half-life so how can you get "mind blowing pumps that last hours"?
All I'm saying is that I would like answers to these 2 questions before I drop $50 on one of the myriad of arginine supplements (and you should too).
If you truly want to increase the blood flow to your muscles then I have a cheap and even more effective way to increase blood flow to your muscles - dextrose/whey. Can it be that simple? Yup.
Tipton et. Al (2001) showed that an amino acid/carbohydrate increased blood flow 300% when taken before the workout and blood flow remained elevated by 30% up to one hour following the completion of the workout. Think about it and save your money.
2. Creatine Ethyl Ester
Much like arginine supplements the scientist in me is weary about this supplement. We all know how our bodies handle creatine monohydrate. There are hundreds of studies out there proclaiming all its benefits. Will our bodies treat CEE the same? I don't know.
One of the big claims to creatine ethyl ester is that it is absorbed better so you don't get the "creatine bloat". The "creatine bloat" is often due to the poor solubility of creatine.
One of the problems with creatine supplements is that all the labels tell you to dissolve your creatine in 12 oz of ice cold water. This is the complete opposite of what you would want to do to a compound that has solubility problems.
To maximize the solubility of your creatine you need to either use more water or use warmer water (both would be best).
Once you do this shake your creatine thoroughly until none settles to the bottom. Then you are ready to drink with no bloat. If you are still having trouble with creatine solubility then I would look into a micronized creatine supplement.
In the end you can buy Creatine Ethyl Ester for $.02 more per gram than regular old creatine monohydrate. So it might be worth a try, but I'm waiting for a little more research.

Final Exam
Now that you have the proper shopping list you can check out your budget and see what you can afford. Just remember the following things
- A great supplement stack won't make up for lazy efforts in the gym.
- Saying you don't have the money to buy the supplements you need when you spend $20 each weekend on beer is a poor excuse.
- Don't be fooled by clever marketing. Stick with time and research proven products that are worth your hard earned money.

mike@muscleandcuts.com
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