Bodybuilding.com - NO Nitric Oxide Information and Product Listing! NO Nitric Oxide FAQ!

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NO Nitric Oxide Info And Products
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1. What is it and where does it come from?
Nitric Oxide is a free form gas that is produced in the body and is used by the body to communicate with other cells in the body. To produce this gas, enzymes in the body break down the amino acid Arginine.

Nitric Oxide is a molecule consisting of one atom of nitrogen and one atom of oxygen. The production of Nitric Oxide occurs when the amino acid L-arginine is converted into L-citruline through an enzyme group known as Nitric Oxide Synthase (NOS). The chemical process of conversion is shown in figure 1.

2. What does it do and what scientific studies give evidence to support this?
Despite the claims of some in the supplement industry, there exists ample scientific literature to suggest the efficacy of Nitric Oxide products. The following was written in May 1996 in a document prepared for the Royal Society and Association of British Science Writers:

Fig. 1 - Click To Enlarge

"Summary research papers continue to flood the scientific journals and insights into the biological activity and potential clinical uses of nitric oxide (NO): a gas controlling a seemingly limitless range of functions in the body. Each revelation adds to nitric oxide's already lengthy resume in controlling the circulation of the blood, regulating activities of the brain, lungs, liver, kidneys, stomach and other organs."

Since the above was written in 1996, Nitric Oxide containing products have continued to be touted by those in the medical profession, as well as by athletes looking to add muscle to their frames.

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The above quotation states that Nitric Oxide controls the circulation of blood, and transmits messages between nerve cells.

The fact that nitric oxide increases blood flow should make it of interest to bodybuilders, as increased blood flow will serve to deliver more nutrients to muscles, thus helping muscles become larger when subject to stress.*

Nitric oxide also affects the endocrine system. It affects the release of gonadotroptin releasing hormone, as well as the release of adrenaline from the adrenal medulla.*

3. Who needs it and what are some symptoms of deficiency?
Everyone REQUIRES nitric oxide to carry out key physiological processes within the body. From a bodybuilder's perspective, nitric oxide supplementation may prove useful in increasing growth due to increases in blood flow to certain areas of the body.*

Signs of deficiency include physical weakness and extreme fatigue. Most "nitric oxide" supplements contain the amino acid Arginine-alpha-keto-glutarate.

4. How much should be taken? Are there any side effects?
With any amino acid containing product, overdose is a possibility. Dosing with too much arginine can lead to diarrhea, weakness and nausea. Clear dosing guidelines have not been established, so it is best to do what is known as "tolerance mapping". Take a small dosage for one week, note the benefits and the side effects, and increase the dosage until the benefits are maximized and the side effects minimized. Over time the two will converge and you will hit the optimal dose. This process is similar to "receptor mapping" for bodybuilders who use insulin.

Many protein powders are fortified with amino acids, including arginine. With this in mind, pay particular attention to how much arginine you are ingesting from all supplements taken.

5. Where can I get it?

At the time of this writing, Pinnacle Brands makes NOx2. This product is very similar to the NO2 product made by MRI. IDS also make a similar product, NP2. With IDS's product, tribulus terrestris is also included. Tribulus is proven to increase testosterone levels.* The combination of tribulus and NO may prove incredibly effective. Other NO products are listed below.

Republished from Clayton South's Health Facts.

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Name - Link Servings Mg Per Serving Price Per Gram Lowest Price

All American EFX Nytric-EFX, 180 Tablets 90 2000 $0.15 $26.99
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Axis Labs NE2, 180 Capsules 60 2250 $0.26 $34.89
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D&E Pump-02, 180 Tablets 60 3000 $0.17 $29.99
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Higher Power AAKG Powder, 1.1 Lbs. 166 3000 $0.05 $25.95
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Higher Power NO-XS, 180 Tablets 60 3500 $0.10 $19.99
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Maximum Nutrients AKG-V-C, 180 Tablets 60 3500 $0.23 $47.95
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Maximum Nutrients AKG-V-C, 90 Tablets 30 3500 $0.26 $26.95
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MRI NO2 Platinum, 180 Caplets 60 3000 $0.33 $59.99
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MRI NO2 Platinum, 300 Caplets 100 3000 $0.28 $84.99
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NOW AAKG 3500, 180 Tablets 60 3500 $0.12 $25.99
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NOW AAKG Powder, 200 Grams 66 3000 $0.11 $21.49
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Optimum Nitric Boost, 180 Tablets 60 3000 $0.16 $28.89
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Pinnacle NoX2, 90 Tablets 30 3000 $0.22 $19.99
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ProFight MegaNO2, 180 Capsules 90 4000 $0.11 $38.99
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SciFit Nitrox, 180 Tablets 60 3500 $0.18 $36.95
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SciFit Nox 3000, 180 Tablets 60 3000 $0.14 $24.99
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Shocker Nutrition N.O. Extreme, 180 Softgels 60 3000 $0.25 $44.89
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Syntrax Nitrous, 303 Grams 60 5000 $0.09 $26.99
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Xyience XNO, 90 Tablets 30 3000 $0.43 $38.95
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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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