Pro-Anabolic Hypertrophic Agent for Intense Muscle Growth!
The primary active anabolic ingredient in Omnibolic is Ecdysterone. Imported directly from Russia, the Ecdysterone in this product is extracted from Rhaponticum carthamoides and is guaranteed to be 98% (or higher) pure. This (and only this) remarkable plant extract, (at this potency), has been suggested in numerous clinical studies to be highly anabolic. Omnibolic is a non-hormonal dietary supplement that will cause a huge increase in anabolism but will not effect hormone levels.
Omnibolic: The Pro-Anabolic Hypertrophic Agent
- Lean Muscle Mass
- Extreme Muscle Definition
- Enhanced Muscle Hardness
- Improved Muscle Density
- Freaky Vascularity
- Increased Strength
- Increased Endurance
Omnibolic works by increasing nitrogen retention and increasing protein synthesis at the cellular level (for this reason we strongly recommend that you increase your daily dietary intake of protein while using this product). It has been suggested that increased nitrogen retention and resistance training will stimulate muscle growth and burn fat as much as 20 times more effective than without the increase in nitrogen retention caused by ecdysterone supplementation. The Russian ingredients in Omnibolic have also been supported to increase in strength and endurance.
How Does Ecdysterone Work?
In each cell there are 3 forms of ribonucleic acid (RNA) which are involved in the production of protein. All of this protein synthesis occurs at the level of the ribosome. Basically, the process involves 3 states:
- Ribosomal RNA (rRNA) gives instructions to the poly-ribosomal complex to join together specific ribosomes into forming a complex (group). This is the manufacturing facility where the proteins and muscle tissue are formed.
- Messenger RNA (mRNA) travels from the nucleus where it has received the specific genetic code on how to make a specific protein. This is very much like a reel-to-reel tape going through a computer in which specific instructions are being given at an extremely rapid rate. The mRNA travels into the poly-ribosomal complex and runs across the ribosomes, giving specific instructions which result in exact sequences of the 22 different amino acids being placed together to form a specific protein (muscle).
- Transfer RNA (tRNA) then move the amino acids to the ribosomes so as to allow the mRNA tape to hook up the individual amino acids to form the polypeptides (protein chains).
6-Keto Diosgenin (25R-Spirost-4-ene-3,6-diol)
Dr. Syrov and Dr. A.J. Kurmukov published a study entitled, "The Experimental Study of the Anabolic Activities of the 6-Keto Derivatives of Some Natural Sapogenins", in which they analyzed the various sterol compounds from these plant sources. They found several adaptogens in addition to the beta-ecdysterone, including agigenin, disogenin and alliogenin, all of which displayed further anabolic activity, but none of which displayed androgenic properties. This basically means that this group of sapogenins do not have any influence in elevating or decreasing the testosterone levels of the person taking them.
Citrulline Malate
Of specific interest to all of us athletes in the trenches is it's role of regulating Nitric Oxide (NO). I mention this first only because the sport nutrition industry has been recently flooded with NO potentiating products comprised of L-Arginine and / or other Arginine salts, which until this day have been the most cost effective manner in improving NO function. It is well known in the scientific community that L-Arginine is a substrate for production of Nitric Oxide, as well as catalyst for other metabolic reactions including its effects on insulin, various hormones and creatine synthesis. (The NO synthase (NOS) enzymes convert Arginine into Citrulline and NO) So what is NO and what can it do for you? Nitric oxide is the cell-signaling molecule that has a part in regulating blood flow, oxygen delivery, glucose uptake, muscle firepower, and muscle growth. Obviously the ability to control these physiological effects can be of tremendous value to athletes.
Unfortunately I think many of the companies currently marketing NO products are missing the boat by not including Citrulline Malate in the current crop of NO supplements. You see, many of Citrulline's functions stem primarily from its ability to increase plasma levels of Arginine endogenously (in the human body). And what is really so exciting about Citrulline is that it seems to increase plasma Arginine levels better than taking the amino acid Arginine itself. You read correctly!
Research suggests that supplementation of Citrulline raises Arginine levels more effectively than taking the same dose of straight Arginine. Keep in mind that Citrulline Malate's NO enhancing properties are just one of the unique benefits this nutrient offers to athletes. And if the enhanced pumps and improved nutrient delivery properties are the reason you are using Arginine based NO products, you need to pay attention to Citrulline Malate.
Increased ATP and Phosphocreatine Recovery
No doubt there is a lot to get excited about when it comes to the performance enhancing potential of Citrulline Malate and how it works. Another study suggested yet another way Citrulline Malate can benefit athletes - by increasing aerobic energy production. Studies suggests subjects using Citrulline Malate have an increase in the rate of muscle ATP (Andenosine Triphosphate, the major energy source within the cell) production during exercise and greater phosphocreatine recovery after exercise. So taking Citrulline Malate may result in muscles that can keep on going and going... completely smashing the aerobic threshold! These effects are more than likely mediated by the malate portion of the Citrulline Malate compound, which is a Krebs Cycle intermediate.
The Krebs Cycle refers to a portion of the metabolic pathway of amino acids in the conversion of sugars and fats into ATP, and the role of friendly bacteria (mitochondria) in our cells. The Krebs Cycle happens in the mitochondria, where sugar and fat pour in and are burned much like in a blast furnace, with a number of weak amino acids acting as a conveyor belt. Impaired ability to make ATP results in premature fatigue and "hitting the wall", unable to continue intense exercise.
Getting back to malate, it appears that it is synergistic when bonded to citrulline and this peptide may work better than supplementation of citrulline alone. While citrulline acts to increase NO and reduce performance inhibiting metabolic toxins, malate conditions the recycling of lactate and pyruvate, and takes part in the kreb cycle supplying instant and sustained energy.
Scientific Studies:
Ecdysterone has been tested for its effects on work capacity, immune function, lean body mass and fat loss, among other variables in a number of scientific studies. The vast majority of research indicates an increase in test subjects' lean mass. Results were further improved when ecdysterone was consumed with protein.
Increase Protein Synthesis
Studies conducted in the Soviet Union in 1988 suggested ecdysterone helps "increase hepatic protein synthesis and subsequently promote positive nitrogen balance!" How does this lead to more muscle mass? Simply: "the more nitrogen your body maintains and the greater rate of protein synthesis, the more mass, period." How, exactly, does ecdysterone do this?
V. Smetanin, researcher of the Smolenk State Medical Institute in Russia speculates that ecdysterone decreases urea concentration in the body and increases hemoglobin levels by increasing a process called erythropoiesis. Erythropoiesis is the development of mature red blood cells. This leads to a stimulation of the anabolic process in protein metabolism, which in turn leads to a positive nitrogen balance in the body.
Increase Lean Muscle While Reducing Body Fat:
The most often quoted ecdysterone scientific study was published in Scientific Sports Bulletin by S. Simakin in 1988. The objective of Simakin's famous study was to determine the effect of ecdysterone on muscle tissue mass and fat mass, while testing for hormonal changes in the subjects. For the study, three control factors were used: a placebo, protein, and ecdysterone with protein. The results were significantly in favor of the third factor. Of the 78 highly trained male and female athletes who consumed just protein, they suggested only a slight increase in muscle mass for the 10 day period of time.
Those who used a placebo lost a slight amount of lean muscle, while those who used protein plus ecdysterone saw a 6-7% increase in lean muscle tissue with nearly a 10% reduction in fat! Let me say that again: A 10% reduction in fat and a 7% increase in lean muscle tissue in just 10 days! Safety testing was conducted during the same time period which saw no difference in hormonal balance. Wow, if ecdysterone plus protein can do this for highly trained athletes, just think what it can do for the average person!
Increase Stamina, Endurance, And Energy:
Ecdysterone was tested in another study performed in 1986 by B.Ya Smetanin. For this research, 117 highly trained speed skaters between the ages of 18 and 28 were tested for work capacity, body weight, lung capacity and VO2 max. The results speak for themselves: all of the said parameters increased as well as an increase in the O2 pulse max and an increase in the exhalation of CO2. Basically, they received more oxygen to their cells! This equates to decreasing recovery time, maximizing performance, permitting optimal muscle anabolism and maximum fat reduction. It also means the athletes using ecdysterone compared to those on a placebo experienced increased stamina, endurance and energy.
That's not all! A study conducted using 112 athletes performed by B.G. Fadeev in Russia suggested some very impressive overall results. However, by this time, the results should come as no surprise. 89% of those who supplemented with ecdysterone versus a placebo reported less fatigue, greater performance, more motivation, greater speed, and improved strength. How long did it take before these athletes reported these effects? Months? Weeks? No, five days. To make matters even better, no adverse side effects were reported.
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